Lipoedema is a painful, chronic disease of the subcutaneous adipose tissue, predominantly affecting women. Conservative complex decongestive therapy is the standard of care but offers limited symptom relief. Liposuction appears to be a promising approach but lacks evidence of effectiveness and safety. The aim of this trial was to show superiority of liposuction compared with conservative therapy regarding relevant pain reduction with reasonable safety. In…
Podda M et al. · Lancet (London, England) · 5 set 2026
Background/Objectives: Non-invasive radiofrequency (NIRF) therapy is increasingly used in physical rehabilitation. However, its efficacy across different lower limb pathologies remains unclear. This study aimed to evaluate the…
Vinolo-Gil MJ et al. · Journal of clinical medicine · 22 mar 2026
Lipedema is a chronic female disease characterized by a painful accumulation of adipose tissue in the limbs. Plasma fatty acid (FA) composition has been proposed as a potential modulator of pain. However, the pathophysiology…
Lundanes J et al. · Nutrition journal · 11 mar 2026
Lipedema is a chronic disorder characterized by abnormal subcutaneous fat accumulation, mainly in women's lower limbs. The aim of the study was to analyze the safety and efficacy of liposuction in treating lipedema. A systematic…
Vengoechea JAA et al. · Aesthetic surgery journal. Open forum · 24 fev 2026
ObjectivesLipedema is a progressive adipose disorder affecting women, with diagnosis often delayed due to symptom overlap and lack of validated tools. This study assesses the Turkish version of the Lipedema Screening…
BackgroundLipedema is a chronic pain disorder characterized by disproportionate adipose tissue accumulation and pain of the affected extremities. While medical compression therapy is recommended for pain reduction, evidence…
BackgroundLipedema is a chronic adipofascial disorder characterized by pain, edema and progressive functional impairment. Conservative treatment is widely recommended as first-line therapy, but evidence on its impact on…
Lipoedema and familial partial lipodystrophy (FPLD) are rare adipose tissue disorders frequently misclassified as common obesity. Clinical assessment and body mass index (BMI) alone may fail to capture regional fat distribution,…
BackgroundLipedema is a chronic condition that is increasingly being detected and gaining public awareness; however, strongly validated therapeutic options are lacking.ObjectivesGiven need for appropriate lipedema management…
Pain and reduced mobility are common among people living with lipoedema. While well-fitting compression garments can help alleviate these symptoms, poorly fitting garments may be ineffective and contribute to significant material…
Murden S, Welsh L, Macintyre L · British journal of community nursing · 26 out 2026
IntroductionLipedema is a chronic adipose and connective tissue disorder in which pain is classically localized to affected limb tissue. However, some patients report joint, periarticular, myotendinous, or axial pain, with…
BackgroundChronic venous disorders and lipedema are complex and frequently underdiagnosed conditions characterized by heterogeneous clinical presentations, progressive tissue remodeling, and substantial variability in treatment…
To evaluate which factors are associated with change in lymphedema-specific quality of life (QoL) and relative volume difference in the maintenance phase after a multidisciplinary intensive treatment program in patients with…
Heroes A et al. · Lymphatic research and biology · 22 out 2026
This Letter to the Editor documents several verifiable internal inconsistencies in the article by Bruno and D'Antimi, including contradictory statements on study design, a level-of-evidence rating incompatible with the stated…
Amato ACM · Aesthetic plastic surgery · 19 out 2026
BackgroundLipedema is a chronic condition that predominantly affects women and is commonly associated with pain, edema, and functional impairment. Conservative physiotherapy interventions are frequently recommended; however, the…
The aim of this study was to characterize global scientific output on lipedema from 2000 to 2025 and identify emerging thematic trends, with emphasis on the emergence of immunological research. Publications indexed in Google…
Amato ACM, Amato JLS, Benitti DA · Revista da Associacao Medica Brasileira (1992) · 16 out 2026